The Department of Pathology and Cell Biology at Columbia University Irving Medical Center seeks a highly qualified researcher with knowledge in molecular oncology and cytoskeletal remodeling using state-of-the art cell biology approaches to apply to cellular and animal models of medulloblastoma. The candidate should be able to carry out research with limited PI supervision both collaboratively and independently. The candidate should have at least 4 years of experience of bench and mouse work and be skilled in communicating their research through regular formal and informal presentations.

At CUIMC, we stand together because diverse experiences, perspectives, and values enrich every dimension of our work. Join our team and see how your unique skills and experiences can create a real impact by changing lives.

Job Function:

• The candidate will need to apply knowledge in molecular oncology and cytoskeletal remodeling using state-of-the art imaging and biochemical approaches using cellular and animal models of medulloblastoma

  The candidate is required to work independently and in collaboration with the other members of the lab

  The candidate will be responsible for breeding and genotyping their own mouse colonies

  The candidate will share responsibility of common lab equipment maintenance with other members of the team

  The candidate will meet with the PI on a weekly basis to communicate the progress of their project informally and monthly or bi monthly to formally communicate their project progress in lab or group meetings

Lab Mission/Purpose:

The overarching goal of our research is to decipher the role of microtubule dynamics and tubulin modifications in synaptic plasticity and neurological disease. Our work is anchored in examining microtubule and tubulin biology in synapses and neuronal compartments using cellular and mouse models of CNS and PNS disease and has recently expanded into decoding these changes in primary glia cells, medulloblastoma models, human cortical neurons reprogrammed from iPS isogenic cell lines carrying disease mutations, and in the acute brain slice. By combining tubulin biochemistry and microtubule biology with molecular and behavioral neuroscience in animal models of disease, my lab is uniquely positioned to work at the interface of cell biology and the pathophysiology of neurodegenerative and neuropathic disease.

Minimum Education Requirements:

Bachelor's degree in cell biology and/or molecular oncology and 4 years of lab experience

Minimum Skills Required:

• Molecular biology techniques
• Animal handling, breeding and genotyping
• Confocal microscopy
• Skills in ImageJ, Prism, PowerPoint softwares
• Science communication

Preferred Qualifications:

Experience with mouse work

Hiring Salary Range:

Staff Associate II: $60,255-$60,255