Apply for Job Job ID366745 LocationAll Other -See Job Description Job FamilyResearch Full/Part TimeFull-Time Regular/TemporaryRegular Job Code9791BD Employee ClassAcad Prof and Admin Add to Favorite Jobs Email this Job About the Job The Liu Lab focuses on understanding the genetic and epigenetic mechanisms underlying human diseases and identifying targetable signaling pathways to drive advancements in cancer therapies. We are seeking a highly motivated Researcher 5 with a strong background in cancer research and expertise in cell biology and mouse model systems. The Researcher 5 will lead and manage multiple innovative research projects centered on TXNIP (Thioredoxin-Interacting Protein), a key regulator of cellular metabolism, oxidative stress, and tumorigenesis. These projects include developing advanced in vivo models, conducting in vitro genetic and pharmacological screens to identify regulators of TXNIP expression and function, and characterizing TXNIP-interacting partners and downstream target genes. Research efforts will involve working with mammalian cell culture, animal models, and clinical specimens. Technical responsibilities include cellular and molecular biology assays, immunohistochemistry and gene expression analysis, flow cytometry and flow sorting, omics studies (transcriptomics and proteomics), microscopy and imaging techniques, drug screening and testing, and orthotopic transplantation tumor models. The candidate will work under general supervision while collaborating closely with the principal investigator to achieve research objectives. The Liu Lab offers an innovative and collaborative environment, providing ample resources and mentorship to support professional development and scientific excellence. The successful candidate will be self-motivated, possess excellent interpersonal skills, and demonstrate the ability to manage multiple and shifting priorities and deadlines. In-depth research expertise is essential to solve complex problems, optimize experimental approaches, and recommend best practices, all of which are critical to success in this role. Focus of Job Responsibilities Research/Project Management - 75% * Design, implement and evaluate multifaceted research projects using state-of-the-art technological and scientific developments. * Assist in the development of short- and long-range lab goals, scientific techniques, and clinical research protocols. Assess needs, evaluate feasibility, and provide input to facilitate implementation. * Conducts research investigations from experimental design and reagent preparation to interpretation of experimental results. * Responsible for analysis of data images to derive parameters which can be compared between samples. * Collect the parameters and prepare them for analysis in the form of graphs. * Consult and participate with other researchers within the lab and other outside units. * Mentor and train undergraduate students, volunteers, and interns. * Provide customized and knowledgeable guidance, complex problem solving and information to researchers. * Conduct independent literature searches to identify emerging tools, analytical methods, data collection systems and software needed to support research projects. * Analyze and present data as graphs and tables using appropriate software to explain findings to investigators and for publication in peer-reviewed journals. * Maintain records on lab arrangements, meeting discussions and other required documentation. Scientific writing - 15% * Generate figures and visual content for manuscripts and grant proposals. * Draft and edit manuscripts for submission to peer-reviewed biomedical journals. * Prepare research proposals for internal and external funding applications. Research training and career development - 5% * Expand expertise in research techniques relevant to the lab's objectives through interactions with the PI, lab personnel, workshops, courses, and seminars. * Participate in national and internationa research meetings and other professional development opportunities. Lab management and supervision - 5% * Support the PI and lab members in maintaining a safe, clean, and efficient laboratory environment. * Assist with laboratory logistics, including receiving, ordering, and inventory management as needed. * Develop and update standard operating procedures (SOPs) for the lab. * Independently manage administrative tasks with minimal guidance. * Assist in supervising and training new lab members and research interns. The Research and Innovation Office (RIO) and The Hormel Institute endorses a "work with flexibility" approach that offers a welcoming and flexible work environment where everyone is inspired to do their best. Work location options include working fully remote, partially remote, or entirely in the office and are based on the work of the position. Some on-site work may be necessary for certain positions, even those designated as fully remote. Because we are a land-grant institution that serves the state, the University will continue to- in most cases- expect employees to live in Minnesota. This position has been designated as eligible for Flexible Work Profile One. Flexible Work Profile One is expected to work primarily on-site. Your office will be located at The Hormel Institute in Austin, MN. The Hormel Institute management retains the right to modify flexible work arrangement agreements on a temporary or permanent basis for any reason at any time. Qualifications Required Qualifications * Advanced degree with one or more years of research training. * Experience in cell and molecular biology, cell culture techniques, and animal models. * Excellent writing and communication skills. Preferred Qualifications * A Ph.D. or equivalent degree in cancer biology, cell biology, or a related field * Minimum of 3 years of postdoctoral research experience and a demonstrated record of impactful publications and/or success in securing research funding. * Proven ability to independently manage research projects with minimal oversight from the principal investigator. * Expertise in omics data analysis (e.g., transcriptomic and proteomic datasets) is highly desirable. About the Department The Hormel Institute is an independent biomedical research institution within the University of Minnesota's Research and Innovation Office. Established in 1942, our mission is to conduct research and provide education in the biological sciences with applications in medicine and agriculture, specifically by understanding, treating, and controlling cancer and other chronic diseases. The Hormel Institute serves as a center of technical and educational expertise for the benefit of the local community, the State of Minnesota, and beyond. We are located in the uniquely diverse rural community of Austin, MN, conveniently only 35 miles from Rochester, MN, and 100 miles (1.5 hours) south of Minneapolis/St. Paul. The Hormel Institute is committed to fostering a work environment that promotes inclusive excellence, supportive employee practices, and encourages diversity of thought that drives... For full info follow application link. The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds. The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu.