Position Summary

A postdoctoral Research Associate position is available in the laboratory of Dr. Eunhee Yi () at Michigan State University. We investigate the molecular mechanisms behind the extrachromosomal DNA (ecDNA)'s oncogenic behaviors, which is well known as a cause of tumor heterogeneity and therapy resistance in cancers. We utilize a high-throughput image-based genetic screening platform to identify potential mechanisms.

Successful candidates will lead a project to investigate the therapy resistance mechanisms of ecDNA-containing cancer cells and develop a novel way to overcome drug resistance in ecDNA-harboring cancers.

Candidates must have a recent Ph.D. degree in a related field along with lead-author publications in top-tier journals, excellent communication and organization skills, and the ability to work independently within a research team. Candidates who pursue an independent career path are highly preferred. Expertise in cancer biology, molecular biology, cell biology, and biochemistry is also desirable. We will provide a competitive salary at the NIH postdoctoral stipend level, excellent benefits, and one-on-one mentoring for a successful research career.

This is a full-time, 12-month fixed-term position with reappointment contingent on satisfactory performance and available funding.

Equal Employment Opportunity Statement

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, age, disability or protected veteran status.

Required Degree

Doctorate -Cancer Biology, Molecular and Cell Biology, Biochemistry, or related field

Minimum Requirements

Candidates must have a Ph.D. or equivalent degree in cancer biology, molecular biology, cell biology, biochemistry, or related fields and lead-author publications in top-tier peer-reviewed journals.

Desired Qualifications

Expertise in cancer research, molecular biology, biochemistry, cancer genomics, high-throughput genetic screening, high-resolution microscopy, image analysis, and/or bioinformatics are desired.

Required Application Materials

Interested candidates should submit:

• a cover letter,
• CV, and
• the contact information of three referees.

Special Instructions

Review of applications begins on 10/25/2023

Review of Applications Begins On

10/25/2023

Summary of Health Risks

Some projects require working with animals or unfixed animal tissue as well as exposure to human blood, serum, tissue, and other body fluids; and materials covered under Universal Precautions.

Website

http://www.yilaboratory.com

Department Statement

The discipline of physiology is uniquely positioned among the biomedical sciences to span the gulf between exploring the most fundamental aspects of biology and the most practical and applied problems of human and animal health. Faculty in the Physiology Department at Michigan State University work to understand how the vast array of molecular and cellular events successfully integrate to define the phenomenon of human existence.

The Physiology Department Mission:

• Identify factors and molecules that promote health and disease.
• Understand mechanisms of disease progression.- Improve overall human and animal health through identification of novel therapeutic targets and treatments.
• Train future scientists in state of the art physiology concepts & approaches.

The Department of Physiology at Michigan State University embraces diversity in its faculty, students and staff. We are committed to providing an environment that nurtures and values inclusion of different backgrounds, ideas, perspectiv